Research

1. Sensitive Bio-detection with a Plasmonic Chip

 
1. Keiko Tawa*, Fusanori. Kodo, Chisato Sasakawa, Kousuke Nagae, Yukito Nakamura, Akitoshi Nozaki, Takatoshi Kaya, “Sensitive Detection of a Tumor Marker, α‑Fetoprotein, with a Sandwich Assay on a Plasmonic Chip,” Analytical Chemistry, 87(7), 3871–3876 (2015). 10.1021/ac504642j
2. M. Tsuneyasu, C. Sasakawa,N. Naruishi, Y. Tanaka, Y. Yoshida, K. Tawa*, “Sensitive detection of interleukin-6 (IL-6) on a plasmonic chip by grating-coupled surface-plasmon-field-enhanced fluorescence imaging”, Japanese Journal of Applied Physics, 53, 06JL05 (2014). 10.7567/JJAP.53.06JL05
3. Keiko Tawa*, Mitsuo Umetsu, Hikaru Nakazawa, Takamitsu Hattori, and Izumi Kumagai “Application of 300× Enhanced Fluorescence on a Plasmonic Chip Modified with a Bispecific Antibody to a Sensitive Immunosensor”, ACS Appl. Mater. Interfaces, 5 (17), 8628–8632 (2013).
4. K. Tawa*, M. Satoh, K. Uegaki, T. Hara, M. Kojima, H. Aota, Y. Yokota, T. Nakaoki, M. Umetsu, H. Nakazawa, I. Kumagai, “Rapid and sensitive detection of brain-derived neurotrophic factor (BDNF) with a plasmonic chip” Jap. J. Appl. Phys., 52(6), 06GK01 1 -5 (2013).
 

2. Sensitive Fluorescence Microscopic Imaging of Cells with a Plasmonic Chip

 

1. Keiko Tawa*, Chikara Yasui, Chie Hosokawa, Hiroyuki Aota and Junji Nishii, ”In Situ Sensitive Fluorescence Imaging of Neurons Cultured on a Plasmonic Dish Using Fluorescence Microscopy”, ACS Appl. Mater. Interfaces, 6 (22), 20010–20015 (2014).
2. XQ. Cui, K. Tawa*, K. Kintaka, and J. Nishii “Enhanced Fluorescence Microscopic Imaging by Plasmonic Nanostructrues: From 1D Grating to 2D Nanohole Array” Adv. Funct. Mater. 20, 945-950 (2010).
3. XQ. Cui, K. Tawa*, H. Hori, and J. Nishii “Tailored Plasmonic Gratings for Enhanced Fluorescence Detection and Microscopic Imaging” Adv. Funct. Mater. 20, 546-553 (2010).
4. K. Tawa*, H. Hori, K. Kintaka, K. Kiyosue, Y. Tatsu, and J. Nishii, “Optical microscopic observation of fluorescence enhanced by grating-coupled surface plasmon resonance” Optics Express, 16, 9781-9790 (2008).

Detection Marker : AFP, EGFR, IL-6, BDNF etc.

Cell: Neuronal cell, MCF-7, MDA-MB231, etc.

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